3-Anilinomethyl-5-chloro-1,3-benzoxazol-2(3H)-one
نویسندگان
چکیده
In the title compound, C(14)H(11)ClN(2)O(2), the 2,3-dihydro-1,3-benzoxazole ring system is essentially planar [maximum deviation = 0.009 (2) Å] and makes a dihedral angle of 79.15 (7)° with the phenyl ring. Inter-molecular N-H⋯O and weak C-H⋯Cl hydrogen bonds occur in the crystal structure.
منابع مشابه
Synthesis and biological activity of novel series of 1,3-benzoxazol-2(3H)-one derivatives.
In the search for novel biological agents, a series of new derivatives N-substituted 1,3-benzoxazol-2(3H)-one, 5-chloro-1,3-benzoxazol-2(3H)-one, 6-bromo-1,3-benzoxazol-2(3H)-one were prepared. All of the compounds were characterized by 1H NMR, 13C NMR and ESI MS spectra. Moreover, for compound 1 an Xray structure was determined. All derivatives were tested for antimicrobial activity against a ...
متن کاملNew fluorescence probes for biomolecules.
Steady state fluorescence measurements have been used for the investigation of interaction between the bovine serum albumin (BSA) and fluorescence probes: 3-hydroxy-2,4- bis[(3-methyl-1,3-benzoxazol-2(3H)-ylidene)methyl]cyclobut-2-en-1-one (SQ6), 3-hydroxy- 2,4-bis[(3-methyl-1,3-benzothiazol-2(3H)-ylidene)methyl]cyclobut-2-en-1-one (SQ7) and 3-hydroxy-2,4-bis[(1,3,3-trimethyl-1,3-dihydro-2H-ind...
متن کامل3-Benzyl-6-(2-chlorobenzoyl)-1,3-benzoxazol-2(3H)-one
In the title compound, C(21)H(14)ClNO(3), the benzoxazolone ring system is planar (r.m.s. deviation = 0.022 Å) and forms dihedral angles of 75.38 (10) and 65.92 (13)° with the mean planes of the chloro-benzoyl (r.m.s. deviation = 0.045 Å, excluding O atom) and benzyl (r.m.s. deviation = 0.023 Å) groups. The observed structure is stabilized by weak C-H⋯O hydrogen bonds and weak inter-molecular C...
متن کاملSynthesis and screening of antibacterial and antifungal activity of 5-chloro-1,3-benzoxazol-2(3 h)-one derivatives
UNLABELLED BACKGROUND An antibacterial is a substance that either kills bacteria or slows their growth. Antifungal are the agents that use drugs for treatment of fungal infections. 5-Chloro-1,3-benzoxazol-2(3 H)-one (5-Chloro Benzoxazolinone) contains an azole ring structure. Numbers of azole compounds are reported as antibacterial and antifungal agents. Benzoxazolinones naturally occur in p...
متن کاملSynthesis and Bioevaluation of 4-[(2/4-chloro-/2, 3-dichloro-/2/4-bromo-/2, 4-dinitro-/4-nitrophenyl) Anilinomethyl]-6-t-butyl-2H-1-benzopyran-2-ones
Synthesis of 4-[(2/4-chloro-/2,3-dichloro-/2/4-bromo-/2,4-dinitro-/4-nitrophenyl) anilinemethyl]6-t-butyl-2H-1-benzopyran-2-ones have been carried out. Synthesized compounds were characterized by 1HNMR, IR and other physical and analytical data. All of the synthesized compounds were evaluated for their antifungal activity against Aspergillus awamori and Sclerotium rolfsii and antibacterial acti...
متن کامل